HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine, 4-(chloroacetyl)- → HCID 66626861, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine, 4-(chloroacetyl)- | HCID 74040 | — |
| Reactant | Pivalic acid 6-{2-[(3-fluoro-4-hydroxybenzoyl)methylamino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester | HCID 66626888 | — |
| Product | HCID 66626861 | HCID 66626861 | 39.8% |
Reaction Steps
Synthesized from pivalic acid 6-{2-[(3-fluoro-4-hydroxybenzoyl)methylamino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester (20 mg) and 2-chloro-1-morpholin-4-ylethanone (13 mg) according to an analogous synthetic method to Example 404 and purified by LC-MS, the title compound (8.2 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07612114B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-b42e476e3a624d6baefb7d233d09c7a8 |
| Source note | uspto-grants-2009_11 |