Tert-butyl 1,4-diazepane-1-carboxylate → 4-[4-(3-Piperidin-1-yl-propoxy)-benzyl]-[1,4]diazepane-1-carboxylic acid tert-butyl ester

HRID 1434566Notes

Reaction equation

HRID 1434566 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:14][CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].C(OC(N1CCN([CH2:28][C:29]2[CH:34]=[CH:33][C:32]([O:35][CH2:36][CH2:37][CH2:38][N:39]3[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40]3)=[CH:31][CH:30]=2)CC1)=O)(C)(C)C>>[C:1]([O:5][C:6]([N:8]1[CH2:14][CH2:13][CH2:12][N:11]([CH2:28][C:29]2[CH:30]=[CH:31][C:32]([O:35][CH2:36][CH2:37][CH2:38][N:39]3[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40]3)=[CH:33][CH:34]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 2756058Tert-butyl 1,4-diazepane-1-carboxylateHCID 686973194-[4-(3-Piperidin-1-yl-propoxy)benzyl]-piperazine-1-carboxylic acid tert-butyl ester

Product 1

HCID 102964254-[4-(3-Piperidin-1-yl-propoxy)-benzyl]-[1,4]diazepane-1-carboxylic acid tert-butyl ester

Procedure

The title compound (D3) was prepared from [1,4]diazepane-1-carboxylic acid tert-butyl ester using the method of Description 1 (D1).

Sources & evidence

ORD record
ord-44602ae7320d42e986aeaa2feaf0f3b7
Source dataset
uspto-grants-2009_11
Patent number
US07615550B2

Reaction notes

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