HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl[4-({4-[(piperidin-4-yl)oxy]phenyl}methyl)piperazin-1-yl]methanone → 1-{4-[4-(1-Isopropyl-piperidin-4-yloxy)-benzyl]-piperazin-1-yl}-1-phenyl-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl[4-({4-[(piperidin-4-yl)oxy]phenyl}methyl)piperazin-1-yl]methanone | HCID 57935703 | — |
| Reactant | 4-[4-(3-Piperidin-1-yl-propoxy)benzyl]-piperazine-1-carboxylic acid tert-butyl ester | HCID 68697319 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-{4-[4-(1-Isopropyl-piperidin-4-yloxy)-benzyl]-piperazin-1-yl}-1-phenyl-methanone | HCID 57935825 | — |
Reaction Steps
The title compound (E33) was prepared from 1-phenyl-1-{4-[4-(piperidin-4-yloxy)-benzyl]-piperazin-1-yl}-methanone (E32) and acetone using the method described in Description 1 (D1). MS(ES+) m/e 422 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615550B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-dd0c23205c24477e829f3b7fbaf3b14b |
| Source note | uspto-grants-2009_11 |