HCID 68705102, compound → HCID 57935964, compound

HRID 1434597Notes

Reaction equation

HRID 1434597 reaction equation
FC(F)(F)S(N1CCC(/C=C/C(O)=O)CC1)(=O)=O.[F:19][C:20]1[CH:21]=[C:22]([C@@H:27]([CH:31]2[CH2:36][CH2:35][N:34]([S:37]([C:40](F)(F)F)(=[O:39])=[O:38])[CH2:33][CH2:32]2)[CH2:28][CH:29]=[O:30])[CH:23]=[C:24]([F:26])[CH:25]=1>>[F:19][C:20]1[CH:21]=[C:22]([C@@H:27]([CH:31]2[CH2:32][CH2:33][N:34]([S:37]([CH3:40])(=[O:39])=[O:38])[CH2:35][CH2:36]2)[CH2:28][CH:29]=[O:30])[CH:23]=[C:24]([F:26])[CH:25]=1

Participants

3

Reactant 2

HCID 68705102HCID 68705102, compoundHCID 86622559HCID 86622559, compound

Product 1

HCID 57935964HCID 57935964, compound

Procedure

In a similar manner but starting from (2E)-3-[1-(trifluoromethylsulfonyl)piperidin-4-yl]acrylic acid in step 1 was prepared (3R)-3-(3,5-difluorophenyl)-3-[1-(trifluoromethylsulfonyl)piperidin-4-yl]propanal.

Sources & evidence

ORD record
ord-f213594497054e579f6817527dd04e18
Source dataset
uspto-grants-2009_11
Patent number
US07615555B2

Reaction notes

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