3-Chloro-2-(p-tolyl)pyridine → HCID 178527198, compound

HRID 1434719Notes

Reaction equation

HRID 1434719 reaction equation
Cl[C:2]1[C:3]([C:8]2[CH:19]=[CH:18][C:11]3[C:12]([OH:17])=[N:13][S:14](=[O:16])(=[O:15])[C:10]=3[CH:9]=2)=[N:4][CH:5]=[CH:6][CH:7]=1.CC1C=CC(C2C([C:33]([F:36])([F:35])[F:34])=CC=CN=2)=CC=1.ClC1C(C2C=CC(C)=CC=2)=NC=CC=1>>[F:34][C:33]([F:36])([F:35])[C:2]1[C:3]([C:8]2[CH:19]=[CH:18][C:11]3[C:12]([OH:17])=[N:13][S:14](=[O:16])(=[O:15])[C:10]=3[CH:9]=2)=[N:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 207099363-Chloro-2-(p-tolyl)pyridineHCID 220303732-p-Tolyl-3-trifluoromethyl-pyridineHCID 178527199HCID 178527199, compound

Product 1

HCID 178527198HCID 178527198, compound

Procedure

The title compound was prepared using the procedures as described for the preparation of the product of Example 1B, substituting the product of Example 7A for the product of Example 1A. MS (DCI+) m/z 329 (M+H)+; 1H NMR (DMSO-d6) δ 7.77 (m, 1H), 7.94 (d, J 7.8, 1H), 8.05 (d, J 7.8, 1H), 8.17 (s, 1H), 8.40 (dd, J 1.3, 7.8, 1H), 8.97 (d, J 4.7, 1H).

Sources & evidence

ORD record
ord-2b87f144071849b0a44f7191963f461b
Source dataset
uspto-grants-2009_11
Patent number
US07615570B2

Reaction notes

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