4-Tert-Butylaniline → HCID 11705436, compound

HRID 1434725Notes

Reaction equation

HRID 1434725 reaction equation
ClC1[C:3]([C:8]2[CH:19]=[CH:18][C:11]3[C:12](O)=[N:13][S:14](=[O:16])(=[O:15])[C:10]=3[CH:9]=2)=[N:4][CH:5]=[CH:6][CH:7]=1.[F:20][C:21]([F:33])([F:32])[S:22]([C:25]1[CH:30]=[CH:29][C:28]([NH2:31])=[CH:27][CH:26]=1)(=[O:24])=[O:23].C(C1C=CC([NH2:42])=CC=1)(C)(C)C>>[N:42]1[CH:7]=[CH:6][CH:5]=[N:4][C:3]=1[C:8]1[CH:19]=[CH:18][C:11]2[C:12]([NH:31][C:28]3[CH:27]=[CH:26][C:25]([S:22]([C:21]([F:32])([F:20])[F:33])(=[O:23])=[O:24])=[CH:30][CH:29]=3)=[N:13][S:14](=[O:15])(=[O:16])[C:10]=2[CH:9]=1

Participants

4

Reactant 3

HCID 698614-Tert-ButylanilineHCID 1363154-Aminophenyl trifluoromethyl sulphoneHCID 178527199HCID 178527199, compound

Product 1

HCID 11705436HCID 11705436, compound

Procedure

The title product was prepared using the procedure as described in Example 1C, substituting the product of Example 24A for the product of Example 1B, and substituting 4-trifluoromethanesulfonyl-phenylamine for 4-tert-butylaniline. 1H NMR (300 MHz, DMSO-d6) δ 7.63 (t, J=4.9 Hz, 1H), 8.29 (m, 2H), 8.39 (m, 2H), 8.70 (d, J=8.1 Hz, 1H), 8.86 (s, 1H), 8.95 (dd, J=8.1, 1.4 Hz, 1H), 9.05 (d, J=5.1 Hz, 2H), 11.46 (s, 1H).

Sources & evidence

ORD record
ord-19aa7c050afd4239b591a40db1d03a1b
Source dataset
uspto-grants-2009_11
Patent number
US07615570B2

Reaction notes

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