HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1H-Pyrrole-2-carboxylic acid, 5-methyl-, ethyl ester → 5-Methyl-4-(3-naphthalen-2-yl-acryloyl)-1H-pyrrole-2-carboxylic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1H-Pyrrole-2-carboxylic acid, 5-methyl-, ethyl ester | HCID 96598 | — |
| Edukt | 3-(Naphthalen-2-yl)prop-2-enoyl chloride | HCID 53928395 | — |
| Produkt | 5-Methyl-4-(3-naphthalen-2-yl-acryloyl)-1H-pyrrole-2-carboxylic acid ethyl ester | HCID 66922127 | — |
Reaktionsschritte
5-Methyl-4-(3-naphthalen-2-yl-acryloyl)-1H-pyrrole-2-carboxylic acid ethyl ester (132) was synthesized from 5-methyl-1H-pyrrole-2-carboxylic acid ethyl ester (107) and 3-naphthalen-2-yl-acryloyl chloride following the procedure described in Example 32. Reaction conditions: 1,2-dichloromethane/−40° C.→RT. Purification: no purification. LC/MS: 40%.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07615572B2 |
| Quelldatensatz | uspto-grants-2009_11 |
| ORD ID | ord-767c2c36ed944b82b2dc4f1cb60998c8 |
| Quellennotiz | uspto-grants-2009_11 |