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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1434808Generated: November 1, 2026

1H-Pyrrole-2-carboxylic acid, 5-methyl-, ethyl ester → HCID 57561739, compound

https://huagongshe.com/reaction/1434808

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Pyrrole-2-carboxylic acid, 5-methyl-, ethyl esterHCID 96598—
Reactant2-(2-Naphthyl)acetyl chlorideHCID 588115—
ProductHCID 57561739HCID 57561739—

Reaction Steps

5-Methyl-4-(2-naphthalen-2-yl-acetyl)-1H-pyrrole-2-carboxylic acid ethyl ester (135) was synthesized from 5-methyl-1H-pyrrole-2-carboxylic acid ethyl ester (107) and naphthalen-2-yl-acetyl chloride following the procedure described in Example 32. Reaction Conditions: 1,2-dichloromethane/−40° C.→RT. Purification: no purification. LC/MS: 80%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615572B2
Source datasetuspto-grants-2009_11
ORD IDord-b2ffccc4dea14b9583fa95395cd0802c
Source noteuspto-grants-2009_11