HRID1434833

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11557851

3-amino-N-(5-chloropyridin-2-yl)pyridine-2-carboxamide

C11H9ClN4O

结构：CC(C)(C)OC(=O)NCCOc1cc(S(C)(=O)=O)ccc1C(=O)O

HCID57936628

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)NCCOc1cc(S(C)(=O)=O)ccc1C(=O)Nc1cccnc1C(=O)Nc1ccc(Cl)cn1

HCID57936590

未命名化合物

收率 84%

PROCEDURE

实验过程

Using a procedure analogous to Example 1-G, 2-(2-t-butoxycarbonylaminoethoxy)-4-methylsulfonylbenzoic acid and 3-amino-N-(5-chloropyridin-2-yl)pyridine-2-carboxamide gave the desired product as a solid (4.0 g, 84%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a2576482fd224d7e99e09d6322e833a3
来源数据集: uspto-grants-2009_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07615568B2
来源说明: uspto-grants-2009_11

反应 SMILES

[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][O:11][C:12]1[CH:20]=[C:19]([S:21]([CH3:24])(=[O:23])=[O:22])[CH:18]=[CH:17][C:13]=1[C:14]([OH:16])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[NH2:25][C:26]1[C:27]([C:32]([NH:34][C:35]2[CH:40]=[CH:39][C:38]([Cl:41])=[CH:37][N:36]=2)=[O:33])=[N:28][CH:29]=[CH:30][CH:31]=1>>[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][O:11][C:12]1[CH:20]=[C:19]([S:21]([CH3:24])(=[O:23])=[O:22])[CH:18]=[CH:17][C:13]=1[C:14]([NH:25][C:26]1[C:27]([C:32]([NH:34][C:35]2[CH:40]=[CH:39][C:38]([Cl:41])=[CH:37][N:36]=2)=[O:33])=[N:28][CH:29]=[CH:30][CH:31]=1)=[O:16])=[O:7])([CH3:2])([CH3:3])[CH3:4]