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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1434836Generated: October 31, 2026

3-amino-N-(5-chloropyridin-2-yl)pyridine-2-carboxamide → 3-[2-(2-tert-Butoxycarbonylaminoethoxy)-4-(methylthio)-benzoylamino]-N-(5-chloropyridin-2-yl)pyridine-2-carboxamide

https://huagongshe.com/reaction/1434836

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-amino-N-(5-chloropyridin-2-yl)pyridine-2-carboxamideHCID 11557851—
Reactant2-(2-Tert-butoxycarbonylaminoethoxy)-4-(methylthio)benzoic acidHCID 57936572—
Product3-[2-(2-tert-Butoxycarbonylaminoethoxy)-4-(methylthio)-benzoylamino]-N-(5-chloropyridin-2-yl)pyridine-2-carboxamideHCID 5793655079%

Reaction Steps

Using a procedure analogous to Example 1-G, 2-(2-tert-butoxycarbonylaminoethoxy)-4-(methylthio)benzoic acid and 3-amino-N-(5-chloropyridin-2-yl)pyridine-2-carboxamide gave the desired product as a solid (4.0 g, 79%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615568B2
Source datasetuspto-grants-2009_11
ORD IDord-110eac1762c445a08c0bb02af3984ff8
Source noteuspto-grants-2009_11