HRID1434837

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11557851

3-amino-N-(5-chloropyridin-2-yl)pyridine-2-carboxamide

C11H9ClN4O

结构：CSc1ccc(C(=O)O)c(OCCCNC(=O)OC(C)(C)C)c1

HCID57936540

未命名化合物

PRODUCTS

生成物

结构：CSc1ccc(C(=O)Nc2cccnc2C(=O)Nc2ccc(Cl)cn2)c(OCCCNC(=O)OC(C)(C)C)c1

HCID68981203

未命名化合物

PROCEDURE

实验过程

Using a procedure analogous to Example 1-G, 2-(3-tert-butoxycarbonylaminopropoxy)-4-(methylthio)benzoic acid and 3-amino-N-(5-chloropyridin-2-yl)pyridine-2-carboxamide gave the desired product as a solid which was purified by HPLC (2.2 g, 28%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f4c71312ead84cc5bb26e02c3e72e312
来源数据集: uspto-grants-2009_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07615568B2
来源说明: uspto-grants-2009_11

反应 SMILES

[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:21]=[C:20]([S:22][CH3:23])[CH:19]=[CH:18][C:14]=1[C:15]([OH:17])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[NH2:24][C:25]1[C:26]([C:31]([NH:33][C:34]2[CH:39]=[CH:38][C:37]([Cl:40])=[CH:36][N:35]=2)=[O:32])=[N:27][CH:28]=[CH:29][CH:30]=1>>[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:21]=[C:20]([S:22][CH3:23])[CH:19]=[CH:18][C:14]=1[C:15]([NH:24][C:25]1[C:26]([C:31]([NH:33][C:34]2[CH:39]=[CH:38][C:37]([Cl:40])=[CH:36][N:35]=2)=[O:32])=[N:27][CH:28]=[CH:29][CH:30]=1)=[O:17])=[O:7])([CH3:2])([CH3:3])[CH3:4]