HCID 136336076, compound → HCID 178502587, compound

HRID 1434839Notes

Reaction equation

HRID 1434839 reaction equation
[C:1]([O:5][C:6]([NH:8][C@H:9]1[CH2:14][CH2:13][C@H:12]([OH:15])[CH2:11][CH2:10]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].O[C:17]1[CH:26]=[C:25]([CH3:27])[CH:24]=[CH:23][C:18]=1[C:19]([O:21][CH3:22])=[S:20]>>[C:1]([O:5][C:6]([NH:8][C@@H:9]1[CH2:10][CH2:11][C@H:12]([O:15][C:17]2[CH:26]=[C:25]([CH3:27])[CH:24]=[CH:23][C:18]=2[C:19]([O:21][CH3:22])=[S:20])[CH2:13][CH2:14]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 136336076HCID 136336076, compoundHCID 178418329HCID 178418329, compound

Product 1

HCID 178502587HCID 178502587, compoundYield 16%

Procedure

Using a procedure analogous to Example 1-D, trans-4-(t-butoxycarbonylamino)cyclohexanol and methyl 2-hydroxy-4-methylthiobenzoate gave the title compound as a white solid (16.0 g, 16%).

Sources & evidence

ORD record
ord-4aaeb2bba7a8440689595259a788abcf
Source dataset
uspto-grants-2009_11
Patent number
US07615568B2

Reaction notes

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