3-Amino-N-(5-chloropyridin-2-yl)-6-methylpyridine-2-carboxamide → HCID 68981399, compound

HRID 1434870Notes

Reaction equation

HRID 1434870 reaction equation
[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:21]=[C:20]([S:22][CH2:23][CH3:24])[CH:19]=[CH:18][C:14]=1[C:15]([OH:17])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[NH2:25][C:26]1[C:27]([C:33]([NH:35][C:36]2[CH:41]=[CH:40][C:39]([Cl:42])=[CH:38][N:37]=2)=[O:34])=[N:28][C:29]([CH3:32])=[CH:30][CH:31]=1>>[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:21]=[C:20]([S:22][CH2:23][CH3:24])[CH:19]=[CH:18][C:14]=1[C:15]([NH:25][C:26]1[C:27]([C:33]([NH:35][C:36]2[CH:41]=[CH:40][C:39]([Cl:42])=[CH:38][N:37]=2)=[O:34])=[N:28][C:29]([CH3:32])=[CH:30][CH:31]=1)=[O:17])=[O:7])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 234387333-Amino-N-(5-chloropyridin-2-yl)-6-methylpyridine-2-carboxamideHCID 57936530HCID 57936530, compound

Product 1

HCID 68981399HCID 68981399, compoundYield 67%

Procedure

Using a procedure analogous to Example 1-G, 2-(3-t-butoxycarbonylaminopropoxy)-4-(ethylthio)benzoic acid and 3-amino-N-(5-chloropyridin-2-yl)-6-methylpyridine-2-carboxamide gave the title compound as a solid (2.2 g, 67%).

Sources & evidence

ORD record
ord-85f42a1862bd4ac481d8023c91d2f169
Source dataset
uspto-grants-2009_11
Patent number
US07615568B2

Reaction notes

Loading…