3-amino-N-(5-chloropyridin-2-yl)pyridine-2-carboxamide → HCID 68982081, compound

HRID 1434873Notes

Reaction equation

HRID 1434873 reaction equation
[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:21]=[C:20]([S:22][CH2:23][CH2:24][CH3:25])[CH:19]=[CH:18][C:14]=1[C:15]([OH:17])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[NH2:26][C:27]1[C:28]([C:33]([NH:35][C:36]2[CH:41]=[CH:40][C:39]([Cl:42])=[CH:38][N:37]=2)=[O:34])=[N:29][CH:30]=[CH:31][CH:32]=1>>[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:21]=[C:20]([S:22][CH2:23][CH2:24][CH3:25])[CH:19]=[CH:18][C:14]=1[C:15]([NH:26][C:27]1[C:28]([C:33]([NH:35][C:36]2[CH:41]=[CH:40][C:39]([Cl:42])=[CH:38][N:37]=2)=[O:34])=[N:29][CH:30]=[CH:31][CH:32]=1)=[O:17])=[O:7])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 115578513-amino-N-(5-chloropyridin-2-yl)pyridine-2-carboxamideHCID 57936589HCID 57936589, compound

Product 1

HCID 68982081HCID 68982081, compound

Procedure

Using a procedure analogous to Example 1-G, 2-(3-t-butoxycarbonylaminopropoxy)-4-(propylthio)benzoic acid and 3-amino-N-(5-chloropyridin-2-yl)pyridine-2-carboxamide gave the title compound as a solid product (2.82 g, 90%).

Sources & evidence

ORD record
ord-b20953c1bf3c4c5ba5d986ba2eb56859
Source dataset
uspto-grants-2009_11
Patent number
US07615568B2

Reaction notes

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