tert-butyl N-(3-hydroxypropyl)carbamate → HCID 57936625, compound

HRID 1434879Notes

Reaction equation

HRID 1434879 reaction equation
[CH3:1][S:2][CH2:3][C:4]1[CH:13]=[CH:12][C:7]([C:8]([O:10][CH3:11])=[O:9])=[C:6]([OH:14])[CH:5]=1.[C:15]([O:19][C:20]([NH:22][CH2:23][CH2:24][CH2:25]O)=[O:21])([CH3:18])([CH3:17])[CH3:16]>>[CH3:1][S:2][CH2:3][C:4]1[CH:13]=[CH:12][C:7]([C:8]([O:10][CH3:11])=[O:9])=[C:6]([O:14][CH2:25][CH2:24][CH2:23][NH:22][C:20]([O:19][C:15]([CH3:16])([CH3:18])[CH3:17])=[O:21])[CH:5]=1

Participants

3

Reactant 2

HCID 3838134tert-butyl N-(3-hydroxypropyl)carbamateHCID 57936580HCID 57936580, compound

Product 1

HCID 57936625HCID 57936625, compoundYield 76%

Procedure

Using a procedure analogous to Example 1-D, methyl 4-(methylthiomethyl)-2-hydroxybenzoate and 3-(t-butoxy-carbonylamino)propanol gave the title compound as a white solid (2.70 g, 76%).

Sources & evidence

ORD record
ord-80b4aba4db944ae2967a8ccf92009aa3
Source dataset
uspto-grants-2009_11
Patent number
US07615568B2

Reaction notes

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