3-Amino-N-(5-chloropyridin-2-yl)-6-methylpyridine-2-carboxamide → HCID 57936546, compound

HRID 1434880Notes

Reaction equation

HRID 1434880 reaction equation
[CH3:1][S:2][CH2:3][C:4]1[CH:12]=[CH:11][C:7]([C:8]([OH:10])=O)=[C:6]([O:13][CH2:14][CH2:15][CH2:16][NH:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH:5]=1.[NH2:25][C:26]1[C:27]([C:33]([NH:35][C:36]2[CH:41]=[CH:40][C:39]([Cl:42])=[CH:38][N:37]=2)=[O:34])=[N:28][C:29]([CH3:32])=[CH:30][CH:31]=1>>[CH3:1][S:2][CH2:3][C:4]1[CH:12]=[CH:11][C:7]([C:8]([NH:25][C:26]2[C:27]([C:33]([NH:35][C:36]3[CH:41]=[CH:40][C:39]([Cl:42])=[CH:38][N:37]=3)=[O:34])=[N:28][C:29]([CH3:32])=[CH:30][CH:31]=2)=[O:10])=[C:6]([O:13][CH2:14][CH2:15][CH2:16][NH:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH:5]=1

Participants

3

Reactant 2

HCID 234387333-Amino-N-(5-chloropyridin-2-yl)-6-methylpyridine-2-carboxamideHCID 57936522HCID 57936522, compound

Product 1

HCID 57936546HCID 57936546, compoundYield 71%

Procedure

Using a procedure analogous to Example 1-G, 2-[4-methylthiomethyl-2-[3-(t-butoxycarbonylamino)propoxy]benzoic acid and 3-amino-6-methyl-N-(5-chloropyridin-2-yl)pyridine-2-carboxamide gave the title compound as a white glassy solid (1.41 g, 71%).

Sources & evidence

ORD record
ord-2cbf4dc4fda54489ad3f5e894d216349
Source dataset
uspto-grants-2009_11
Patent number
US07615568B2

Reaction notes

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