反应详情

The nitro derivative from Step B (100 mg, 0.283 mmol) was dissolved in 10 ml of ethanol and hydrogenated with Raney-nickel for 18 hours. The catalyst was then filtered off and the solution was heated to reflux for 3 hours. After evaporation, the crude product was purified by preparative HPLC. Yield: 19 mg (23%).

1. filtrationThe catalyst was then filtered off
2. temperaturethe solution was heated
3. temperatureto reflux for 3 hours
4. customAfter evaporation
5. customthe crude product was purified by preparative HPLC