HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-2,2,6,6-tetramethylpiperidine → 1-{5-[2-(2,2,6,6-Tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-thiophen-2-yl}-propan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-2,2,6,6-tetramethylpiperidine | HCID 37524 | — |
| Reactant | 2,4-Dichloropyrimidine | HCID 77531 | — |
| Reactant | alpha-Methyl-2-thiopheneethanol | HCID 98093 | — |
| Product | 1-{5-[2-(2,2,6,6-Tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-thiophen-2-yl}-propan-2-ol | HCID 11176286 | — |
Reaction Steps
The title compound was prepared analogous to Steps B and C of Method A, starting from 1-thiophen-2-yl-propan-2-ol, 2,4-dichloro-pyrimidine and 2,2,6,6-tetramethyl-piperidin-4-ylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615562B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-678e9124b051460ca67d63b33091c19c |
| Source note | uspto-grants-2009_11 |