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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1434929Generated: October 27, 2026

2-Methyl-1-(thiophen-2-yl)propan-2-ol → 2-Methyl-1-{5-[2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-thiophen-2-yl}-propan-2-ol

https://huagongshe.com/reaction/1434929

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-1-(thiophen-2-yl)propan-2-olHCID 11073666—
Reactant(4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amineHCID 57936167—
Product2-Methyl-1-{5-[2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-thiophen-2-yl}-propan-2-olHCID 11429173—

Reaction Steps

The title compound was prepared analogous to Method C, starting from (4-chloro-pyrimidin-2-yl)-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine and 2-methyl-1-thiophen-2-yl-propan-2-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615562B2
Source datasetuspto-grants-2009_11
ORD IDord-901a37fea3c04565b50e57c338a15e8d
Source noteuspto-grants-2009_11