(4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amine → HCID 11487198, compound

HRID 1434934Notes

Reaction equation

HRID 1434934 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][CH:7]1[CH2:9][CH:8]1[C:10]([OH:13])([CH3:12])[CH3:11].Cl[C:15]1[CH:20]=[CH:19][N:18]=[C:17]([NH:21][CH:22]2[CH2:27][C:26]([CH3:29])([CH3:28])[NH:25][C:24]([CH3:31])([CH3:30])[CH2:23]2)[N:16]=1>>[CH3:28][C:26]1([CH3:29])[CH2:27][CH:22]([NH:21][C:17]2[N:16]=[C:15]([C:5]3[S:1][C:2]([CH2:6][CH:7]4[CH2:9][CH:8]4[C:10]([OH:13])([CH3:11])[CH3:12])=[CH:3][CH:4]=3)[CH:20]=[CH:19][N:18]=2)[CH2:23][C:24]([CH3:31])([CH3:30])[NH:25]1

Participants

3

Reactant 2

HCID 57936167(4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amineHCID 57936332HCID 57936332, compound

Product 1

HCID 11487198HCID 11487198, compoundYield 20%

Procedure

The title compound was prepared analogous to Method C, starting from 2-(2-thiophen-2-ylmethyl-cyclopropyl)-propan-2-ol and (4-chloro-pyrimidin-2-yl)-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine. Yield: 20%.

Sources & evidence

ORD record
ord-b8f383892e464ec5aa3e7f10591c211b
Source dataset
uspto-grants-2009_11
Patent number
US07615562B2

Reaction notes

Loading…