(4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amine → HCID 11166703, compound

HRID 1434935Notes

Reaction equation

HRID 1434935 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH:8][CH:9]2[CH2:14][C:13]([CH3:16])([CH3:15])[NH:12][C:11]([CH3:18])([CH3:17])[CH2:10]2)[N:3]=1.[CH3:19][C:20]([OH:32])([C:22]([CH3:31])([CH3:30])[CH2:23][CH2:24][C:25]1[S:26][CH:27]=[CH:28][CH:29]=1)[CH3:21]>>[CH3:21][C:20]([OH:32])([C:22]([CH3:31])([CH3:30])[CH2:23][CH2:24][C:25]1[S:26][C:27]([C:2]2[CH:7]=[CH:6][N:5]=[C:4]([NH:8][CH:9]3[CH2:14][C:13]([CH3:16])([CH3:15])[NH:12][C:11]([CH3:18])([CH3:17])[CH2:10]3)[N:3]=2)=[CH:28][CH:29]=1)[CH3:19]

Participants

3

Reactant 2

HCID 57936167(4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amineHCID 57936302HCID 57936302, compound

Product 1

HCID 11166703HCID 11166703, compound

Procedure

The title compound was prepared analogous to Method C, starting from (4-chloro-pyrimidin-2-yl)-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine and 2,3,3-trimethyl-5-thiophen-2-yl-pentan-2-ol from Step A.

Sources & evidence

ORD record
ord-8fe0639f3c434d4fb4d658ee6bcaf4c3
Source dataset
uspto-grants-2009_11
Patent number
US07615562B2

Reaction notes

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