(4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amine → HCID 11475938, compound

HRID 1434936Notes

Reaction equation

HRID 1434936 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH:8][CH:9]2[CH2:14][C:13]([CH3:16])([CH3:15])[NH:12][C:11]([CH3:18])([CH3:17])[CH2:10]2)[N:3]=1.[CH2:19]([O:21][C:22]([CH3:31])([CH3:30])[C:23]([C:25]1[S:26][CH:27]=[CH:28][CH:29]=1)=[O:24])[CH3:20]>>[CH2:19]([O:21][C:22]([CH3:30])([CH3:31])[C:23]([C:25]1[S:26][C:27]([C:2]2[CH:7]=[CH:6][N:5]=[C:4]([NH:8][CH:9]3[CH2:14][C:13]([CH3:16])([CH3:15])[NH:12][C:11]([CH3:18])([CH3:17])[CH2:10]3)[N:3]=2)=[CH:28][CH:29]=1)=[O:24])[CH3:20]

Participants

3

Reactant 2

HCID 57936167(4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amineHCID 69067760HCID 69067760, compound

Product 1

HCID 11475938HCID 11475938, compound

Procedure

The title compound was prepared analogous to Method C, starting from (4-chloro-pyrimidin-2-yl)-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine and 2-ethoxy-2-methyl-1-thiophen-2-yl-propan-1-one.

Sources & evidence

ORD record
ord-83e36f9f27ee4991adf382026f7f98e4
Source dataset
uspto-grants-2009_11
Patent number
US07615562B2

Reaction notes

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