3-(Tributylstannyl)pyridine → HCID 11257899, compound

HRID 1434948Notes

Reaction equation

HRID 1434948 reaction equation
Br[C:2]1[S:6][C:5]([C:7]2[CH:12]=[CH:11][N:10]=[C:9]([NH:13][CH:14]3[CH2:19][C:18]([CH3:21])([CH3:20])[NH:17][C:16]([CH3:23])([CH3:22])[CH2:15]3)[N:8]=2)=[CH:4][CH:3]=1.C([Sn](CCCC)(CCCC)[C:29]1[CH:30]=[N:31][CH:32]=[CH:33][CH:34]=1)CCC>>[N:31]1[CH:32]=[CH:33][CH:34]=[CH:29][C:30]=1[C:2]1[S:6][C:5]([C:7]2[CH:12]=[CH:11][N:10]=[C:9]([NH:13][CH:14]3[CH2:19][C:18]([CH3:21])([CH3:20])[NH:17][C:16]([CH3:23])([CH3:22])[CH2:15]3)[N:8]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 34838483-(Tributylstannyl)pyridineHCID 57936128{4-[5-Bromothiophen-2-yl]-pyrimidin-2-yl}-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine

Product 1

HCID 11257899HCID 11257899, compoundYield 13%

Procedure

The title compound was prepared as described for Example 25, using [4-(5-bromo-thiophen-2-yl)-pyrimidin-2-yl]-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine (Step C of Example 5) and 3-tributylstannylpyridine. Yield: 13%.

Sources & evidence

ORD record
ord-e57259163fe9485988dddbe7e13966cf
Source dataset
uspto-grants-2009_11
Patent number
US07615562B2

Reaction notes

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