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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1434956Generated: October 25, 2026

4-Amino-2,2,6,6-tetramethylpiperidine → 1-{5'-[5-Methyl-2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-[2,2']bithiophenyl-5-yl}-ethanone

https://huagongshe.com/reaction/1434956

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-2,2,6,6-tetramethylpiperidineHCID 37524—
ReactantPyrimidine, 2,4-dichloro-5-methyl-HCID 74508—
Reactant5-Acetyl-2,2'-bithienylHCID 606422—
Product1-{5'-[5-Methyl-2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-[2,2']bithiophenyl-5-yl}-ethanoneHCID 11305580—

Reaction Steps

The title compound was prepared analogous to Method A, starting from 1-[2,2′]bithiophenyl-5-yl-ethanone, 2,4-dichloro-5-methyl-pyrimidine and 4-amino-2,2,6,6-tetramethylpiperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615562B2
Source datasetuspto-grants-2009_11
ORD IDord-68f7aa3afb2e462382d46eee149c1bb2
Source noteuspto-grants-2009_11