Acetic Anhydride → HCID 57936277, compound

Participants

Reaction Steps

Compound of Example 86 (119 mg, 0.3 mmol) was dissolved in 5 ml THF and 0.5 ml triethylamine and 36 μl (0.33 mmol) acetic anhydride were added. This mixture was stirred at room temperature for 16 hours. Afterwards the solution was diluted with 100 ml water and extracted with EtOAc. The crude was purified by chromatography on silicagel (DCM/MeOH/ammonia:9/1/0.1). Yield: 103 mg (78%).

Provenance & Evidence