huagongshe.com
HRID1434984

反应详情

EQUATION

反应方程式

HRID 1434984 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)CC(N)CC(C)(C)N1
HCID37524

2,2,6,6-Tetramethylpiperidin-4-amine

C9H20N2

结构：CS(=O)c1nccc(-c2ccc(Br)cc2)n1
HCID57936175

未命名化合物

PRODUCTS

生成物

1
结构：CC1(C)CC(Nc2nccc(-c3ccc(Br)cc3)n2)CC(C)(C)N1
HCID57936126

未命名化合物

PROCEDURE

实验过程

4-(4-Bromo-phenyl)-2-methanesulfinyl-pyrimidine (0.25 g, 0.84 mmol) and 4-amino-2,2,6,6,-tetramethylpiperidine (1 ml) were heated for 45 minutes at 130° C. Evaporation and chromatography on silicagel (EtOAc/MeOH/ammonia:95/4.5/0.5 to 90/9/1) gave the title compound as white crystals. Yield: 260 mg (78%).

WORKUP

后处理

  1. customEvaporation and chromatography on silicagel (EtOAc/MeOH/ammonia:95/4.5/0.5 to 90/9/1)