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HRID1435001

反应详情

EQUATION

反应方程式

HRID 1435001 的结构方程式

REACTANTS

反应物

3
结构：N
HCID222

Ammonia gas

H3N

结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：CC1(C)CC(Nc2nccc(-c3ccc(CCC(=O)O)cc3)n2)CC(C)(C)N1
HCID57936234

未命名化合物

PRODUCTS

生成物

1
结构：CC1(C)CC(Nc2nccc(-c3ccc(CCC(N)=O)cc3)n2)CC(C)(C)N1
HCID57936263

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

The title compound was prepared from 3-{4-[2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-phenyl}-propionic acid (Step A of Example 185) and thionyl chloride followed by ammonia in MeOH. Yield: 5.3 mg (11%).