HuagongsheHuagongshe Chemistry Print Report · For research reference only
{4-[4-(3-Azido-butyl)-phenyl]-pyrimidin-2-yl}-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine → {4-[4-(3-Amino-butyl)-phenyl]-pyrimidin-2-yl}-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {4-[4-(3-Azido-butyl)-phenyl]-pyrimidin-2-yl}-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine | HCID 57936133 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | {4-[4-(3-Amino-butyl)-phenyl]-pyrimidin-2-yl}-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine | HCID 57936270 | — |
Reaction Steps
The title compound was prepared from {4-[4-(3-azido-butyl)-phenyl]-pyrimidin-2-yl}-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine by hydrogenation using PtO2 in MeOH. Yield: 39 mg (87%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615562B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-b19a6a0972444bda907ea01e396f8b03 |
| Source note | uspto-grants-2009_11 |