Sodium borohydride → HCID 57936239, compound

HRID 1435016Notes

Reaction equation

HRID 1435016 reaction equation
[CH3:1][C:2]1([CH3:27])[CH2:7][CH:6]([NH:8][C:9]2[N:14]=[C:13]([C:15]3[CH:20]=[CH:19][C:18]([CH2:21][C:22](=[O:24])[CH3:23])=[CH:17][CH:16]=3)[CH:12]=[CH:11][N:10]=2)[CH2:5][C:4]([CH3:26])([CH3:25])[NH:3]1.[BH4-].[Na+]>CO>[CH3:26][C:4]1([CH3:25])[CH2:5][CH:6]([NH:8][C:9]2[N:14]=[C:13]([C:15]3[CH:20]=[CH:19][C:18]([CH2:21][CH:22]([OH:24])[CH3:23])=[CH:17][CH:16]=3)[CH:12]=[CH:11][N:10]=2)[CH2:7][C:2]([CH3:27])([CH3:1])[NH:3]1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 57936231HCID 57936231, compound

Product 1

HCID 57936239HCID 57936239, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The title compound was prepared by reduction of {4-[2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-phenyl}-propan-2-one with sodium borohydride in MeOH. Yield: 32 mg (100%).

Sources & evidence

ORD record
ord-590d389527aa42f5bc9ba155a1f4015d
Source dataset
uspto-grants-2009_11
Patent number
US07615562B2

Reaction notes

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