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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1435050Generated: November 3, 2026

Tetrabutylammonium Fluoride → HCID 57936281, compound

https://huagongshe.com/reaction/1435050

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrabutylammonium FluorideHCID 2724141—
Reactant(4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amineHCID 57936167—
ReactantHCID 69065385HCID 69065385—
ProductHCID 57936281HCID 57936281—

Reaction Steps

The title compound was prepared as described in Example 215, starting from 5-fluoro-1-(2-trimethylsilanyl-ethoxymethyl)-1H-indole (prepared by SEM protection of 5-fluoro-1H-indole using standard procedures) and (4-chloro-pyrimidin-2-yl)-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine, followed by cleavage of the SEM protecting group with TBAF.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615562B2
Source datasetuspto-grants-2009_11
ORD IDord-9d3e653840814fbcbe9e4e89b3747ff1
Source noteuspto-grants-2009_11