HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Ethyl 2-mercapto-2-methylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Propanoic acid, 2-bromo-2-methyl-, ethyl ester | HCID 11745 | — |
| Reactant | Sodium hydrosulfide hydrate | HCID 16211346 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 2-mercapto-2-methylpropanoate | HCID 14181802 | 36% |
Reaction Steps
Ethyl 2-bromoisobutyrate (48.8 g, 0.250 mole), sodium hydrosulfide hydrate (84 g, 1.5 mole), water (100 mL), ethyl alcohol (200 mL). Let reaction mix stir at room temperature. Next day, no starting material observed. Crude yield: 74.3%; distillation yield: 36.0%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615661B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-e75733b00fb949a88f3a90873c089504 |
| Source note | uspto-grants-2009_11 |