HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 44227492, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propanoic acid, 2-bromo-2-methyl-, ethyl ester | HCID 11745 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | tert-Amylthiol | HCID 15511 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 44227492 | HCID 44227492 | — |
Reaction Steps
Ethyl 2-bromoisobutyrate (33.9 g, 0.174 mole), 2-methyl-2-butanethiol (20.0 g, 0.192 mole), potassium hydroxide (12.2 g, 0.192 mole), ethyl alcohol (100 g) were combined and the reaction mixture was refluxed for approximately 10 hours prior to quenching. Crude yield: 63.5%; after column chromatography 18.1%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615661B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-55043752c00040d6a292038d20b6adfa |
| Source note | uspto-grants-2009_11 |