HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanethiol → Ethyl 2-methyl-2-(methylthio)propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanethiol | HCID 878 | — |
| Reactant | Propanoic acid, 2-bromo-2-methyl-, ethyl ester | HCID 11745 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 2-methyl-2-(methylthio)propionate | HCID 3016499 | — |
Reaction Steps
Ethyl 2-bromoisobutyrate (40.0 g, 0.205 mole), methanethiol (1.09 g, 0.0226 mole), potassium hydroxide (14.4 g, 0.226 mole,), ethyl alcohol (100 g), refluxed reaction mixture until peak for ethyl 2-bromoisobutyrate is no longer detectable by gas chromatography. Distill to purify.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615661B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-35e90e1e545e41219c9811519f9f33ff |
| Source note | uspto-grants-2009_11 |