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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1435107Generated: November 2, 2026

HCID 54695617, compound → HCID 68569908, compound

https://huagongshe.com/reaction/1435107

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 54695617HCID 54695617—
ReactantHCID 57937626HCID 57937626—
ProductHCID 68569908HCID 6856990873.3%

Reaction Steps

Title compound (2.2 g) was prepared from methyl 5-(1H-benzimidazol-1-yl)-3-hydroxy-2-thiophenecarboxylate (J. Heterocyclic Chem., 1987, 24, 1301-1303) (1.9 g, 7.0 mmol) and (1S)-1-(2-chloro-3-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}phenyl)ethanol (Intermediate 17, 2.0 g, 7.0 mmol) using a procedure analogous to Intermediate 2, Step C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615643B2
Source datasetuspto-grants-2009_11
ORD IDord-9633f67c773848d3a7a89182699fd28b
Source noteuspto-grants-2009_11