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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1435222Generated: October 26, 2026

1-Bromo-4,5-difluoro-2-methoxybenzene → HCID 11723824, compound

https://huagongshe.com/reaction/1435222

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-4,5-difluoro-2-methoxybenzeneHCID 2736262—
Reactant4-Amino-2-ethylsulfanylpyrimidine-5-carboxylic acid methoxymethylamideHCID 10105787—
ProductHCID 11723824HCID 11723824—

Reaction Steps

The same procedure as described in Example 47 was used, starting from 4-amino-2-ethylsulfanylpyrimidine-5-carboxylic acid methoxymethylamide, Example 1, and 2-bromo4,5-difluoro-anisole (Astatech), to give (4-amino-2-ethylsulfanyl-pyrimidin-5-yl)-(2,3-difluoro-6-methoxy-phenyl)-methanone as a white solid. MS (M+H)+, 326.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615634B2
Source datasetuspto-grants-2009_11
ORD IDord-6d3778cc81324267b77e60df494c64b9
Source noteuspto-grants-2009_11