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HRID1435236

反应详情

EQUATION

反应方程式

HRID 1435236 的结构方程式

REACTANTS

反应物

2
结构：O=S(=O)(Cl)c1ccsc1
HCID2776378

Thiophene-3-sulfonyl Chloride

C4H3ClO2S2

结构：COc1ccc(F)cc1C(=O)c1cnc(NC2CCNCC2)nc1N
HCID9997668

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(F)cc1C(=O)c1cnc(NC2CCN(S(=O)(=O)c3ccsc3)CC2)nc1N
HCID58777610

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from [4-amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone, Example 59, and 3-thiophenesulfonyl chloride (Maybridge) by the procedure described in Example 152. HR-MS (ES, m/z) calculated for C21H23FN5O4S2 [(M+H)+] 492.1170, observed 492.1175.