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HRID1435271

反应详情

EQUATION

反应方程式

HRID 1435271 的结构方程式

REACTANTS

反应物

2
结构：O=S(=O)(Cl)CCCCl
HCID15410

Propanesulfonyl chloride, chloro-

C3H6Cl2O2S

结构：COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCNCC2)nc1N
HCID10316630

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(S(=O)(=O)CCCCl)CC2)nc1N
HCID9983584

未命名化合物

PROCEDURE

实验过程

The compound was prepared from [4-amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanone (Example 107) and chloropropanesulfonyl chloride (Aldrich) in an analogous manner as described in Example 177. HR-MS (ES, m/z) calculated for C20H25N5O4SF2Cl [(M+H)+] 504.1279, observed 504.1284.