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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1435274Generated: November 1, 2026

2-Amino-1-butanol, (-)- → HCID 58777606, compound

https://huagongshe.com/reaction/1435274

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-butanol, (-)-HCID 2723856—
Reactant[4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanoneHCID 9983584—
ProductHCID 58777606HCID 58777606—

Reaction Steps

The compound was prepared from [4-amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanone (Example 226) and (R)-2-amino-1-butanol (Aldrich) in an analogous manner as described in Example 227. HR-MS (ES, m/z) calculated for C24H35N6O5SF2 [(M+H)+] 557.2352, observed 557.2360.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615634B2
Source datasetuspto-grants-2009_11
ORD IDord-fa3b45a6d7784827823f8b7037c65f78
Source noteuspto-grants-2009_11