Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1435286Generated: October 31, 2026

2-Amino-1-butanol, (+)- → HCID 10076407, compound

https://huagongshe.com/reaction/1435286

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-butanol, (+)-HCID 120084—
Reactant[4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanoneHCID 9983584—
ProductHCID 10076407HCID 10076407—

Reaction Steps

The compound was prepared from [4-amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanone (Example 226) and (S)-2-amino-1-butanol (Aldrich) in an analogous manner as described in Example 227. HR-MS (ES, m/z) calculated for C24H35N6O5SF2[(M+H)+] 557.2352, observed 557.2356.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615634B2
Source datasetuspto-grants-2009_11
ORD IDord-57966d22454d4a07b6099167dfd5a651
Source noteuspto-grants-2009_11