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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1435292Generated: November 3, 2026

2-Amino-1-butanol, (-)- → HCID 10370001, compound

https://huagongshe.com/reaction/1435292

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-butanol, (-)-HCID 2723856—
Reactant[4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanoneHCID 10458099—
ProductHCID 10370001HCID 10370001—

Reaction Steps

The compound was prepared from [4-amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone (Example 242) and (R)-2-amino-1-butanol (Aldrich) in an analogous manner as described in Example 227. HR-MS (ES, m/z) calculated for C24H36N6O5SF [(M+H)+]539.2450, observed 539.2447.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615634B2
Source datasetuspto-grants-2009_11
ORD IDord-dc4bb240319c46658114fa12b4013db3
Source noteuspto-grants-2009_11