Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1435293Generated: October 30, 2026

1-Amino-2-propanol → HCID 58777552, compound

https://huagongshe.com/reaction/1435293

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Amino-2-propanolHCID 4—
Reactant[4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanoneHCID 10458099—
ProductHCID 58777552HCID 58777552—

Reaction Steps

The compound was prepared from [4-amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone (Example 242) and 1-amino-2-propanol (Eastman Kodak) in an analogous manner as described in Example 227. HR-MS (ES, m/z) calculated for C23H34N6O5SF [(M+H)+]525.2290, observed 525.2295.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615634B2
Source datasetuspto-grants-2009_11
ORD IDord-e92e6ede17c44063ba090b8ed791af89
Source noteuspto-grants-2009_11