HuagongsheHuagongshe Chemistry Print Report · For research reference only
D-Valinol → HCID 10325324, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | D-Valinol | HCID 6950587 | — |
| Reactant | [4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone | HCID 10458099 | — |
| Product | HCID 10325324 | HCID 10325324 | — |
Reaction Steps
The compound was prepared from [4-amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone (Example 242) and (R)-2-amino-3-methyl-1-butanol (Aldrich) in an analogous manner as described in Example 227. HR-MS (ES, m/z) calculated for C25H38N6O5SF [(M+H)+]553.2603, observed 553.2600.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615634B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-874c7735ff364bffa0c77ca5c0236b1b |
| Source note | uspto-grants-2009_11 |