Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1435298Generated: November 3, 2026

2-Amino-1-butanol, (+)- → HCID 10459894, compound

https://huagongshe.com/reaction/1435298

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-butanol, (+)-HCID 120084—
Reactant[4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanoneHCID 10458099—
ProductHCID 10459894HCID 10459894—

Reaction Steps

The compound was prepared from [4-amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone (Example 242) and (S)-2-amino-1-butanol (Aldrich) in an analogous manner as described in Example 227. HR-MS (ES, m/z) calculated for C24H36N6O5SF [(M+H)+]539.2447, observed 539.2449.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615634B2
Source datasetuspto-grants-2009_11
ORD IDord-17cb0eb35abe4919b0ed2d83a7a3085a
Source noteuspto-grants-2009_11