HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 2-bromo-1,4-dimethoxy- → (4-Amino-2-ethylsulfanyl-pyrimidin-5-yl)-(2,5-dimethoxy-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 2-bromo-1,4-dimethoxy- | HCID 91353 | — |
| Reactant | 5-Pyrimidinecarboxamide, 4-amino-2-(ethylthio)-N-methoxy-N-methyl- | HCID 11974832 | — |
| Product | (4-Amino-2-ethylsulfanyl-pyrimidin-5-yl)-(2,5-dimethoxy-phenyl)-methanone | HCID 21070478 | — |
Reaction Steps
The same procedure as described in Example 47 was used, starting from 4-amino-2-ethylsulfanyl-pyrimidine-5-carboxylic acid methoxy-methyl-amide, (Example 1), and 2-bromo-4-methoxyanisole (Aldrich), to give (4-amino-2-ethylsulfanyl-pyrimidin-5-yl)-(2,5-dimethoxy-phenyl)-methanone as a white solid. MS (M+H)+, 320.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615634B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-397b291fc8fa495584ffeffe939dc36a |
| Source note | uspto-grants-2009_11 |