HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Aminopiperidin-1-yl)ethan-1-one → 1-[4-[4-Amino-5-(4-fluoro-benzoyl)-pyrimidin-2-ylamino]-piperidin-1-yl]-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Aminopiperidin-1-yl)ethan-1-one | HCID 4962477 | — |
| Reactant | HCID 21070564 | HCID 21070564 | — |
| Product | 1-[4-[4-Amino-5-(4-fluoro-benzoyl)-pyrimidin-2-ylamino]-piperidin-1-yl]-ethanone | HCID 21070364 | — |
Reaction Steps
The same procedure as described in Example 326 was used, starting with (4-amino-2-ethanesulfinyl-pyrimidin-5-yl)-(4-fluoro-phenyl)-methanone (Example 366) and 1-(4-amino-piperidin-1-yl)-ethanone to give 1-[4-[4-amino-5-(4-fluoro-benzoyl)-pyrimidin-2-ylamino]-piperidin-1-yl]-ethanone as a white solid. MS (M+H)+, 358.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615634B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-919caef403be4269a633201f69c04113 |
| Source note | uspto-grants-2009_11 |