Toluene → 1-Cyclopropyl-3-(2-fluoro-4-trimethylsilanyl-phenylamino)-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid methyl ester
Reaction equation
[C:37](=[O:38])([O-:39])[O-:40].[CH3:1][O:2][C:3](=[O:4])[c:5]1[c:6]([NH2:17])[c:7]2[cH:8][n:9][cH:10][cH:11][c:12]2[n:13]1[CH:14]1[CH2:15][CH2:16]1.[CH3:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[Cs+:41].[Cs+:42].[F:18][c:19]1[c:20]([O:29][S:30]([C:31]([F:32])([F:33])[F:34])(=[O:35])=[O:36])[cH:21][cH:22][c:23]([Si:25]([CH3:26])([CH3:27])[CH3:28])[cH:24]1.[O:52]=[C:53]([CH:54]=[CH:55][c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1)[CH:62]=[CH:63][c:64]1[cH:65][cH:66][cH:67][cH:68][cH:69]1.[O:70]=[C:71]([CH:72]=[CH:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1)[CH:80]=[CH:81][c:82]1[cH:83][cH:84][cH:85][cH:86][cH:87]1.[O:88]=[C:89]([CH:90]=[CH:91][c:92]1[cH:93][cH:94][cH:95][cH:96][cH:97]1)[CH:98]=[CH:99][c:100]1[cH:101][cH:102][cH:103][cH:104][cH:105]1.[Pd:50].[Pd:51]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[c:6]([NH:17][c:20]2[c:19]([F:18])[cH:24][c:23]([Si:25]([CH3:26])([CH3:27])[CH3:28])[cH:22][cH:21]2)[c:7]2[cH:8][n:9][cH:10][cH:11][c:12]2[n:13]1[CH:14]1[CH2:15][CH2:16]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e4cb48a953e948fc8000e4f523b94508
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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