Water → 7-Bromo-3-fluoro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:20]1)[C:7]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)=[N:8][CH:9]([OH:13])[C:10](=[O:12])[NH:11]2.[CH2:21]([N:22]([S:23]([F:24])([F:25])[F:27])[CH2:26][CH3:28])[CH3:29].[CH2:31]([Cl:32])[Cl:33].[OH2:30]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:20]1)[C:7]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)=[N:8][CH:9]([F:27])[C:10](=[O:12])[NH:11]2Participants
5
Sources & evidence
- ORD record
- ord-47c7750e378847bd9fe940b0f58f72cf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…