HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylamine → N-Cyclopropyl-3-methyl-1H-pyrazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | 5-methyl-1H-pyrazole-4-carboxylic acid | HCID 557600 | — |
| Product | N-Cyclopropyl-3-methyl-1H-pyrazole-4-carboxamide | HCID 178434551 | 94% |
Reaction Steps
Following the same procedure in Example 29 (Step B and C in Method B), using 3-methyl-1H-pyrazole-4-carboxylic acid (252 mg, 2.0 mmol) and cyclopropylamine (285 mg, 5.0 mmol), provided the desired crude compound (310 mg, 94%), which was used in Step A directly.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615642B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-d5aaa8dc38754dff99f27887215f6e2b |
| Source note | uspto-grants-2009_11 |