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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1435617Generated: October 25, 2026

4-Fluorobenzenesulfonyl chloride → Ethyl (2-{[(4-fluorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate

https://huagongshe.com/reaction/1435617

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzenesulfonyl chlorideHCID 9588—
Reactant4-Thiazoleacetic acid, 2-amino-, ethyl esterHCID 104454—
ProductEthyl (2-{[(4-fluorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetateHCID 717529—

Reaction Steps

The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 4-fluorobenzenesulfonyl chloride according to METHOD A, giving 0.29 g (42%) of a pink powder: MS (electrospray, [M−H]−) m/z 343.1

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618961B2
Source datasetuspto-grants-2009_11
ORD IDord-72a061d1cfce4d369fc2d8f61d4f6957
Source noteuspto-grants-2009_11