4-Thiazoleacetic acid, 2-amino-, ethyl ester → HCID 10133640, compound

HRID 1435619Notes

Reaction equation

HRID 1435619 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1.[CH:13]([C:16]1[CH:21]=[CH:20][C:19]([S:22](Cl)(=[O:24])=[O:23])=[CH:18][CH:17]=1)([CH3:15])[CH3:14]>>[CH:13]([C:16]1[CH:21]=[CH:20][C:19]([S:22]([NH:1][C:2]2[S:3][CH:4]=[C:5]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=2)(=[O:24])=[O:23])=[CH:18][CH:17]=1)([CH3:15])[CH3:14]

Participants

3

Reactant 2

HCID 1044544-Thiazoleacetic acid, 2-amino-, ethyl esterHCID 27348824-(Propan-2-yl)benzene-1-sulfonyl chloride

Product 1

HCID 10133640HCID 10133640, compound

Procedure

The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 4-isopropylbenzenesulfonyl chloride according to METHOD A, giving 0.57 g (78%) of a pink powder: MS (electrospray, [M−H]−) m/z 367.2.

Sources & evidence

ORD record
ord-bf999143dced40fda2e61eef7675e5ac
Source dataset
uspto-grants-2009_11
Patent number
US07618961B2

Reaction notes

Loading…